Published Articles

Clinical Study on a New Cream for Sensitive Skin: Combining Traditional and Innovative Ingredients

Authors: Pekmezci, E., Sevinç, H., Türetkan, G., and Türkoğlu, M. (2023)
Aim: The aim of this clinical study is to assess the efficacy of a new cream formulation combining traditional and innovative ingredients for treating sensitive skin.
Findings: The study reported significant improvements in skin conditions associated with dermatitis, highlighting the potential of the new ingredients for sensitive skin care.

Exploring the Benefits of Helichrysum Italicum Extract for Skin Health

Authors: Pekmezci, E., and Türkoğlu, M. (2023)
Aim: This research investigates the dermatological benefits of Helichrysum italicum extract on the extracellular matrix of the skin.
Findings: In vitro tests indicate that the extract promotes beneficial changes, suggesting its potential use in cosmetic formulations aimed at skin health.

Investigating Urtica Dioica Extract’s Effect on Skin Disease-Related Gene Expression

Authors: Pekmezci, E., and Türkoğlu, M. (2023)
Aim: This study explores the impact of Urtica dioica (nettle) extract on gene expression related to androgenic skin diseases.
Findings: The extract was found to significantly downregulate certain gene expressions, indicating a promising avenue for treating androgen-related skin issues.

Comparative Study of Plant Extracts Against Acne Vulgaris

Authors: Kılıç, S., Okullu, S.Ö., Kurt, Ö., Sevinç, H., Dündar, C., Altınordu, F., and Türkoğlu, M. (2019)
Aim: This study evaluates the efficacy of broccoli and cauliflower extracts in treating acne vulgaris.
Findings: The results indicate that both extracts are highly effective against P. acnes and demonstrate anti-inflammatory properties in vitro.

Radish Extract’s Effect on Gene Expression Related to Inflammatory Skin Conditions

Authors: Pekmezci, E., and Türkoğlu, M. (2019)
Aim: This study aims to evaluate the effects of radish (Raphanus sativus) extract on inflammatory gene expression in skin cells.
Findings: In vitro results suggest that the extract downregulates VEGF, TNF-α, and 5α-R2 gene expressions, indicating its potential for treating dermatological inflammatory conditions.

Herbal Anti-Acne Alternative Proves Clinically Effective

Authors: Turkoglu, M., Dundar, C., and Pekmezci, E. (2017)
Aim: This study assesses the clinical effectiveness of botanical extracts for acne treatment compared to traditional options.
Findings: The results demonstrated that broccoli and cauliflower extracts effectively improve acne in vitro and show strong efficacy in clinical settings.

Evaluating New Anti-Dandruff Shampoo Formulations Against Malassezia

Authors: Ergin, Ç., Kurt, Ö., Türkoğlu, M., Sevinç, H., and Akbaba, G. (2024)
Aim: This study aims to evaluate new active ingredient combinations for cosmetic shampoos intended to combat dandruff caused by Malassezia species.
Findings: Preliminary evidence reveals that the novel formulations demonstrate effectiveness against dandruff, showing promise for future anti-dandruff treatments.

New Anti-Dandruff Shampoo Proves More Effective Than Ketoconazole

Authors: Pekmezci, E., and Türkoğlu, M. (2021)
Aim: This clinical study aims to compare the effectiveness of a newly developed anti dandruff shampoo with a standard ketoconazole shampoo.
Findings: The novel formulation demonstrated superior effectiveness, potentially due to the inclusion of thermal mineral water, offering a new alternative for dandruff treatment.

Study on a Herbal Extract for Hair Loss: A Clinical Investigation

Authors: Pekmezci, E., Dündar, C., and Türkoğlu, M. (2018)
Aim: This placebo-controlled clinical study assesses the safety and effectiveness of a proprietary herbal extract for treating hair loss in androgenetic alopecia and telogen effluvium.
Findings: Findings indicate significant improvements in hair density and overall hair health after six months of treatment with the herbal extract.

Comparison of Botanical Extracts to Minoxidil for Hair Growth

Authors: Türkoğlu, M., Dündar, C., Sevinç, H., and Kılıç, S. (2017)
Aim: This comparative study evaluates the effectiveness of a botanical extract against minoxidil in promoting hair growth in human keratinocyte cells.
Findings: Both treatments exhibited anti-androgen effects, suggesting that the botanical extract could be a viable alternative to minoxidil for hair loss treatment.

Effects of Fig Leaf Extract on Hair Loss Parameters

Authors: Turkoglu, M., Pekmezci, E., Kilic, S., Dundar, C., and Sevinc, H. (2017)
Aim: This study investigates the effects of Ficus carica (fig) leaf extract on selected parameters related to hair loss in vitro.
Findings: Results indicate that fig leaf extract provides both anti-androgenic and anti-inflammatory benefits, enhancing its potential for hair loss treatment.

Herbal Extracts and Their Potential Against Alopecia

Authors: Pekmezci, E., Dundar, C., and Turkoglu, M. (2018)
Aim: This study tests the effectiveness of a proprietary herbal extract in combating nonscarring alopecia using an in vitro approach.
Findings: The results showed that the extract significantly downregulates the gene expression of IL-1α, indicating its potential in treating alopecia areata.

Cardioprotective Effects of Date Palm Fruit Against Heart Damage

Authors: Coşkun, R., Çelik, A.İ., Coşgun, M.S., Dündar, C., Türkoğlu, M., and Süleyman, H. (2022)
Aim: This research investigates the cardioprotective effects of Phoenix dactylifera (date palm) fruit extract against oxidative stress in heart tissue.
Findings: Results indicate a significant protective effect against heart muscle damage induced by doxorubicin, suggesting its potential as a food supplement for heart health.

In Vitro Evaluation of Thermal Mineral Waters on Skin Cells

Authors: Karagülle, M.Z., Karagülle, M., Kılıç, S., Sevinç, H., Dündar, C., and Türkoğlu, M. (2018)
Aim: This preliminary study investigates the effects of natural thermal mineral waters on human keratinocyte cells.
Findings: The in vitro research indicates anti-inflammatory effects, suggesting the potential benefits of thermal waters in cosmetic formulations.

The Impact of Sheep Tail Fat on Cartilage Health in Rats

Authors: Cimen, F.K., Kockara, N., Turkoglu, M., Dundar, C., Cetin, N., Suleyman, B., Coban, A., Yarali, O., Malkoc, I., and Suleyman, H. (2017)
Aim: This research examines the effects of sheep tail fat on cartilage injury in rat models induced by formalin.
Findings: The study concludes that sheep tail fat significantly reduces cartilage damage, indicating its potential as a therapeutic food supplement for joint health.